Notification Center is an amazing new feature of the OS X Mountain Lion but is not so useful for those who are not social. If muting notifications sounds still does not do for you, you can disable it. Follow these steps.
* From the Finder, hit CMD + Shift + G keys simultaneously and enter this path: /System/Library/CoreServices/
* Now, find “Notification Center.app” and click on the name and then rename it to “Notification Center-disabled.app”.
* Fire up Terminal and type this:
That is it. You have disabled the notification center.